In this paper with a new measure considering both efficacy and side effect, we developed a new method for identifying the repositioned drugs against prostate ...
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Aug 18, 2012 · Abstract—With the merits of faster development time and reduced risk, identifying new indications for marketed drugs.
May 15, 2018 · Drug repositioning is a promising strategy to identify non-cancer drugs which have anti-cancer activity as well as tolerable adverse effects for human health.
A new method for identifying the repositioned drugs against prostate cancer by evaluating the mutual relations of the gene expression levels between ...
The results led to the prioritization of a set of drugs and/or clinically tested candidates potentially useful in drug repurposing against PC. Keywords: ...
Then, using the curated drug-target interactions from the Therapeutic Target Database [46] and DrugBank, the targets of these drugs were retrieved. A total of ...
Nov 27, 2023 · ... drugs for a new indication in cancer treatment. ... drug development: novel approach to drug target identification and drug repositioning.
The cost and time to develop a drug continues to be a major barrier to widespread distribution of medication. ... The method uses variable gene signatures to ...
A new method to identify repositioned drugs for prostate cancer. Wu, Zikai, Wang, Yong, Chen, Luonan · Details · Contributors · Bibliography · Quotations ...
Currently, available drugs that have been approved for the treatment of CRPC patients are limited. Computational drug repositioning methods using public ...