Abstract. For a genomic region containing a tandem gene cluster, a proper set of alignments needs to align only orthologous segments, i.e.,.
Attaining this goal in practice requires a technique for avoiding a combinatorial explosion in the number of local alignments. To better understand this process ...
For a genomic region containing a tandem gene cluster, a proper set of alignments needs to align only orthologous segments, i.e., those separated by a ...
Dive into the research topics of 'Controlling size when aligning multiple genomic sequences with duplications'. Together they form a unique fingerprint. Sort by ...
Larger CNV size and greater gene number correlate with duplication pathogenicity, consistent with deleterious consequences from extra copies of many genes. In ...
This chapter describes the tools used, and the steps taken, to produce aligned reads from raw sequencing data.
Gene duplication is an important evolutionary mechanism allowing to provide new genetic material and thus opportunities to acquire new gene functions for an ...
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Mar 18, 2022 · Here we introduce a new approach, BISER, to quickly detect SDs in multiple genomes and identify elementary SDs and core duplicons that drive the formation of ...
Whole-genome alignment (WGA) is a critical process in comparative genomics, facilitating the detection of genetic variants and aiding our understanding of ...
LASTZ is designed for pairwise alignments of whole genomes and can efficiently align chromosomal or genomic sequences millions of nucleotides in length. To ...