Early-Stage Chronic Kidney Disease and Hip Fracture Mortality

J Surg Orthop Adv. 2018 Fall;27(3):226-230.

Abstract

Chronic kidney disease (CKD) is a documented risk factor for hip fracture mortality. CKD represents a spectrum of disease and there is no clear evidence differentiating the risk between patients with early versus end-stage CKD. The purpose of this study was to explore the relationship between the stages of CKD and mortality following operative treatment of hip fractures. Four hundred ninety-eight patients were analyzed; 81 were identified as having CKD. This study followed overall patient mortality at 90 days and at 1 year postoperatively. Patients with CKD had higher mortality at both 90 days and 1 year compared with those without CKD (hazard ratio 1.69 and 1.84, respectively). In a subgroup analysis to determine the effect of CKD stage, only stage 3 CKD was associated with increased mortality. The orthopaedic surgeon can play a key role in identifying at-risk patients and help to facilitate additional management. (Journal of Surgical Orthopaedic Advances 27(3):226-230, 2018).

MeSH terms

  • Aged
  • Case-Control Studies
  • Comorbidity
  • Female
  • Fracture Fixation, Internal
  • Hip Fractures / mortality*
  • Hip Fractures / surgery
  • Humans
  • Male
  • Mortality
  • Multivariate Analysis
  • Postoperative Period
  • Proportional Hazards Models
  • Renal Insufficiency, Chronic / epidemiology*
  • Renal Insufficiency, Chronic / metabolism
  • Retrospective Studies
  • Severity of Illness Index