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[PDF] A causal discovery approach for streamline ion channels selection to ...
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May 24, 2023 · This method can accurately classify high TdP-risk drugs through a single analytical assessment considering a unique ionic channel and ...
Causality is of paramount importance in bio-medical data analysis: assessing the causal relationships between the observed variables allows to improve our ...
May 24, 2023 · Discovering causal relations between drug-induced ionic channels' perturbations could shed new light on the underlying mechanisms leading to TdP.
Aug 4, 2024 · Discovering causal relations between drug-induced ionic channels' perturbations could shed new light on the underlying mechanisms leading to TdP ...
Aug 4, 2024 · Torsade de Pointes (TdP) is a serious drug-induced cardiac side effect which can lead to sudden death. TdP is related to abnormal ...
A Causal Discovery Approach to Streamline Ionic Currents Selection to Improve Drug-Induced TdP Risk Assessment. S Al-Ali, J Llopis-Lorente, MT Mora, M Sermesant ...
Oct 14, 2024 · The Comprehensive In-vitro Proarrhythmia Assay (CiPA) initiative aims to refine the assessment of drug-induced torsades de pointes (TdP) ...
A Causal Discovery Approach to Streamline Ionic Currents Selection to Improve Drug-induced TdP Risk Assessment. Request PDF. Restricted access. Profile Image.
Oct 4, 2023 · Torsades de Pointes (TdP) is a prevalent fatal arrhythmia symptom and a key indicator of sudden cardiac death events (Gintant, 2008; Frommeyer ...
Missing: Causal Discovery
We propose a schema for stratifying the risk of marketed QT prolonging drugs based on US Food and Drug Administration (FDA)-approved drug labeling.
Missing: Causal Streamline Selection