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Rethinking the Dose-Response Relationship Between Usage and Outcome in an Online Intervention for Depression: Randomized Controlled Trial

Rethinking the Dose-Response Relationship Between Usage and Outcome in an Online Intervention for Depression: Randomized Controlled Trial

It was hypothesized that usage would be associated with outcome and that modules completed would have the strongest relationship with outcome, consistent with the systematic review by Donkin et al [16]. Cardiovascular Risk E-couch Depression Outcome (CREDO) is a randomized, double-blind, parallel, attention-controlled, Internet-delivered trial targeting depressive symptoms in those with risk factors for or diagnosis of cardiovascular disease (CVD).

Liesje Josephine Donkin, Ian B Hickie, Helen Christensen, Sharon L Naismith, Bruce Neal, Nicole L Cockayne, Nick Glozier

J Med Internet Res 2013;15(10):e231