Version 1
: Received: 27 November 2023 / Approved: 28 November 2023 / Online: 28 November 2023 (11:47:02 CET)
How to cite:
Yang, T.; Chen, X.; Zhao, H.; Ding, X.; Hou, Y. The Structure Characterization and Biological Activities of New Polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P). Preprints2023, 2023111808. https://doi.org/10.20944/preprints202311.1808.v1
Yang, T.; Chen, X.; Zhao, H.; Ding, X.; Hou, Y. The Structure Characterization and Biological Activities of New Polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P). Preprints 2023, 2023111808. https://doi.org/10.20944/preprints202311.1808.v1
Yang, T.; Chen, X.; Zhao, H.; Ding, X.; Hou, Y. The Structure Characterization and Biological Activities of New Polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P). Preprints2023, 2023111808. https://doi.org/10.20944/preprints202311.1808.v1
APA Style
Yang, T., Chen, X., Zhao, H., Ding, X., & Hou, Y. (2023). The Structure Characterization and Biological Activities of New Polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P). Preprints. https://doi.org/10.20944/preprints202311.1808.v1
Chicago/Turabian Style
Yang, T., Xiang Ding and Yiling Hou. 2023 "The Structure Characterization and Biological Activities of New Polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P)" Preprints. https://doi.org/10.20944/preprints202311.1808.v1
Abstract
The structure characterization of two new polysaccharides from Agrocybe aegerita (AA-P) and Hygrophorus olivaceoalbus (HO-P) by HPGPC, GC-MS, NMR and FT-IR indicated that AA-P was composed of Galactose, Glucose and Arabinose, in the ratio of 3:2:1. Its skeleton structure was consisted of (1→4)-Arap, (1→4,6)-Glup and (1→6)-Galp with one branched chain. The HO-P was consisted of mannose, galactose and glucose in a ratio of 1:1:2. Its skeleton structure was consisted of (1→6)-Galactose residues, (→1)-glucose residues, (1→4)-glucose residues and (1→4,6)-D-mannose residues. There were two branched chains connected to the main chain. AA-P and HO-P had the best stimulation effect on B cells and RAW264.7 cells, respectively, and could both mainly by impacting and reducing G0/G1 phase which lead to a significant proliferation of B cells, T cells and RAW264.7 cells. In addition, AA-P and HO-P could significantly promote the secretion of TNF-α from T cells, the secretion of IgA, IgD, IgE, IgG and IgM from B cells, and the secretion of TNF-α from RAW264.7 cells, but neither of them could impact the secretion of IL-1β from RAW264.7 cells.
Biology and Life Sciences, Food Science and Technology
Copyright:
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